Blood

Initial Results from Study Hgb-206: A Phase 1 Study Evaluating Gene Therapy By Transplantation of Autologous CD34+ Stem Cells Transduced Ex Vivo with the Lentiglobin BB305 Lentiviral Vector in Subjects with Severe Sickle Cell Disease.

Blood

Julie Kanter, Mark C. Walters, Matthew Hsieh, Alexis A. Thompson, Lakshmanan Krishnamurti, Janet Kwiatkowski, Rammurti T Kamble, Christof von Kalle, Frans A. Kuypers, Marina Cavazzana, Philippe Leboulch, Laura Sandler, Sandeep Soni, John F. Tisdale

Pan-Selectin Antagonist Rivipansel (GMI-1070) Reduces Soluble E-Selectin Levels While Improving Clinical Outcomes in SCD Vaso-Occlusive Crisis.

Blood

Ted Wun, Marilyn J. Telen, Lakshmanan Krishnamurti, Timothy L. McCavit, Laura M DeCastro, Henry Flanner, Frans A. Kuypers, Sandra K. Larkin, Seungshin Rhee, John L. Magnani, Helen M. Thackray

Microparticles As Biomarkers Of Osteonecrosis Of The Hip In Sickle Cell Disease.

Blood

Anne M Marsh, Raymond Schiffelers, Ginny Gildengorin, Frans A Kuypers, Carolyn Hoppe

Citrate Synthase Activity Is Increased In Children With Sickle Cell Disease (SCD) On Hydroxyurea (HU) Therapy.

Blood

Claudia R. Morris, Cornelia Latronica, Frans A Kuypers, Howard Rosenfeld, Sandra K Larkin, Stephanie Doniger, Elliott Vichinsky, Sruti Shiva

Tricuspid Regurgitant Jet Velocity (TRV), Biomarkers of Hemolysis, and Impact of Oxygen Therapy in Children with Sickle Cell Disease (SCD) and Vaso-Occlusive Pain Episodes (VOE).

Blood

Cornelia Latronica, Frans A Kuypers, Howard Rosenfeld, Sandra K Larkin, Stephanie Doniger, Elliott Vichinsky, Claudia R. Morris

Treatment with a Novel Dinitroazetidine, Abdnaz, Improves Nitrite Reductase Activity of Sickle Red Blood Cells.

Blood

Marcel H.A.M. Fens, Sandra K Larkin, William L Fitch, Jan Scicinski, Bryan Oronsky, Frans A Kuypers

Sildenafil Therapy in Patients with Thalassemia and an Elevated Tricuspid Regurgitant Jet Velocity (TRV) On Doppler Echocardiography At Risk for Pulmonary Hypertension: Report From the Thalassemia Clinical Research Network.

Blood

Claudia R. Morris, Hae-Young Kim, John C Wood, Felicia Trachtenberg, Elizabeth S Klings, John B. Porter, Nancy Sweeters, Nancy F Olivieri, Janet L. Kwiatkowski, Sylvia Titi Singer, Ali T Taher, Ellis J. Neufeld, Alexis A. Thompson, Vandana Sachdev, Sandra K Larkin, Jung H Suh, Frans A Kuypers, Elliott Vichinsky

Pan-Selectin Antagonist GMI-1070 Affects Biomarkers of Adhesion, Activation and the Coagulation Cascade in Sickle Cell Adults At Steady State.

Blood

John L. Magnani, Frans A Kuypers, John T. Patton, Sandra K Larkin, Lori Styles, Laura M DeCastro, Marilyn J. Telen, Ted Wun, Helen Thackray

Cardiopulmonary and Laboratory Profiling of Patients with Thalassemia At Risk for Pulmonary Hypertension: Report From the Thalassemia Clinical Research Network.

Blood

Claudia R. Morris, Hae-Young Kim, John C Wood, Felicia Trachtenberg, Elizabeth S Klings, John B. Porter, Nancy Sweeters, Nancy F Olivieri, Janet L. Kwiatkowski, Sylvia Titi Singer, Ali T Taher, Ellis J. Neufeld, Alexis A. Thompson, Sandra K Larkin, Jung H Suh, Elliott Vichinsky, Frans A Kuypers

NO or No NO, Increased Reduction of Nitrite to Nitric Oxide by Modified Red Blood Cells.

Blood

Marcel H.A.M. Fens, Sandra K Larkin, Claudia R. Morris, Bill Fitch, Jan Scicinski, Bryan Oronsky, Frans A Kuypers

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